Biomarker Gene ID Symbol Drug DrugBank ID target journal PMID
Inhibitor/Promoter ChangingTrends DetectingTechniques year
iNOS 4843 NOS2 na na na Nitric Oxide 16517189 driver increased IHC, RT-PCR, WB 2006
prolidase 5184 PEPD na na collagen Br J Dermatol 16634881 na increased WB 2006
PGE2 na na na na collagen J Invest Dermatol 16528361 driver decreased IHC, WB 2006
TGF-β1 7040 TGFB1, SMAD2 na na na J Invest Dermatol 16498396 driver increased IHC, WB 2006
NNP-1 8568 RRP1 na na na Br J Dermatol 15606508 driver increased cDNA microarray, in situ hybridization 2004
NF-κB 4790 NFKB1 na na antiapoptotic genes Arch Dermatol Res 15278366 driver increased cDNA microarrays, IHC, WB 2004
P38 MAP kinase 1432 MAPK14 na na TGF-β2 Nan Fang Yi Ke Da Xue Xue Bao 16546734 na na RT-PCR, WB 2006
ACE 1636 ACE na na na J Am Acad Dermatol 16443055 driver increased HPLC 2006
HIF-1α 3091 HIF1A Hypoxia na ERK1/2, PI-3K/Akt Exp Cell Res 16289155 driver increased WB, IF 2006
TGF-β 7040 TGFB1, SMAD2 na na Wnt/β-catenin Acta Derm Venereol 16874413 driver na IHC, WB 2006
TGF-β1 7040 TGFB1, SMAD2 na na SMAD6, SMAD7 J Plast Reconstr Aesthet Surg 16676428 na na RT-PCR, WB 2006
TbetaR II 7048 TGFBR2 na na na Zhonghua Zheng Xing Wai Ke Za Zhi 16573164 na variation DNA sequencing 2006
TGF-β 7040 TGFB1, SMAD2 na na CTGF Plast Reconstr Surg 16217483 driver na RT-PCR 2005
TGF-beta1, VEGF 7040, 7422 TGFB1, VEGFA na na na Arch Dermatol Res 16184401 driver increased WB, ELISA 2005
Smad3 4088 SMAD3 na na na J Pathol 16052471 driver na WB 2005
TGF-β3 7043 TGFB3 na na na Br J Plast Surg 16043141 no effect variation DHPLC mutation detection 2005
Hsp47 871 SERPINH1 na na na Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 16130386 na increased qRT-PCR 2005
Etk/Bmx 660 BMX na na VEGF，PAI-1, iNOS Am J Physiol Cell Physiol 15788485 na increased RT-PCR, WB 2005
caspase-9 842 CASP9 na na caspase-3 Wound Repair Regen 16008726 suppressor increased IHC 2005
na na na SB-431542 na TGF-β1 J Dermatol Sci 15978417 suppressor na IF, WB 2005